HUBS1404 Lecture Notes - Lecture 14: Luteal Phase, Corpus Luteum, Endocrine System

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Female reproductive cycle: puberty, pregnancy, timing of birth, menopause. Gnrh - stimulates pituitary to release lh and fsh: males - stimulates testes to release testosterone. Females - stimulates to release estrogens and progesterone. All of these have negative effect on hypothalamus - negative feedback. Lh - has a direct effect on the laydig cells in the seminiferous tubules. Fsh - stimulated process of sermatogenesis and androgen binding - keeps local population of sperm in the testis and promotes spermatogenesis. Aims: to produce 1 ovulated oocyte per cycle. Ovarian cycle (follicular + luteal phase: to produce the right uterine environment for implantation. Luteal phase (ovarian) - controlled by corpus leuteum - secretion of progesterone prevents further ovulation. Secretory phase (uterine) - producing glycogen and other glycoproteins to support a developing embryo. Hormone control of the follicular phase of ovarian cycle. Secondary (fsh/lh: primordial (not under hormonal control, primary (fsh/lh, graffian (lh, oocyte, corpus luteum progesterone.

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