9808 Lecture Notes - Lecture 5: Lysosome, Axial Skeleton, Bone Density

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A tibial-fibular fracture is a fracture of both the tibia and fibula in the lower leg. What changes are occurring to broken bone during healing: fracture hematoma, soft tissue callus, bony callus, bone re-modelling. Bones have a good blood supply, where as cartilage has a relatively poor blood supply. Terminology: os-, osseo-, osteo- = bone, end-, endo- = within, inside, peri- = around, epi- = upon or above, cyte- = cell. 1. support framework that supports body and cradles organs: protection skull protects brain, ribs protect lungs and heart and vertebrae protect spinal cord, movement/leverage skeletal muscle attaches to bone via tendons and bones are the levers for movement. Joints determine what kind of movement we have: mineral and growth factor storage, calcium and phosphate reservoir, marrow and fat storage, blood cell formation, both white and red blood cells are produces in the cavity of bone. Osteolysis: osteolysis is important to maintain calcium (aids in muscle contraction) and phosphate in blood.

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