483 Lecture Notes - Lecture 5: Meiosis, Chromosome, Dihybrid Cross
LECTURE 5
Mendelian inheritance
Concepts in Biology
2018 Semester 1
Simon et al. 2016: pp.178-195. Adrian.Dusting@canberra.edu.au
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Learning objectives
To understand:
–Mendel’s experiments and how they have informed
our modern understanding of genetics
–Monohybrid and dihybrid crosses
–Why a test cross is used in genetic analysis
–Beyond Mendel:
•Incomplete dominance
•Co-dominance
•Multiple-allele traits
•Polygenic inheritance
•Pleiotropy
•The role of the environment
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The Genetics Lexicon
Allele
Trait
Gene
Chromosome
Homologous
Homozygote
Heterozygote
Phenotype
Genotype
…version of…
…has
different…
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Document Summary
Character: a heritable feature that varies among individuals. e. g. eye colour. Trait: a variant of a particular character. e. g. blue eyes: traits are not inherited directly, the appear during development p. 180. Determines a characteristic in organism http://jonesgen564s14. weebly. com/flnb-gene. html: the expression of genes, along with environmental factors, determine the traits observed. p. 83,182. Allele: a version of a gene character traits gene alleles p. 182 eye: rebelcircus. com chromosome: broadinstitute. org. Gregor mendel: mendel was a monk in brno in the 1860s. Studied mathematics, physics and chemistry: interested in how traits are inherited, chose garden peas (pisum sativum) for his inheritance experiments p. 180. Reproduction can be controlled: self- or cross-fertilise, both parents known p. 180. When 2 identical true-breeding individuals are crossed, all offspring have the same characteristics as the parents. Using true-breeding pea varieties allowed him to study the inheritance of one trait at a time pp. 180-183. Mendel: methods: mendel crossed two different true-breeding varieties together.