VETS2006 Lecture Notes - Lecture 4: Immunity (Medical), B Cell, Endothelium

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25 May 2018
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Introduction and Overview of the Immune Response.
Introduction
- Earliest reference to immunity, earliest use of vaccines, earliest understanding of the
specificity of the immune response. See slide for details.
The immune response
- The body is under continual attack from invading organisms (viruses, bacteria, parasites)
- The body also faces internal attack. I.e. Abnormal neoplastic (cancerous) cells that arise
spontaneously.
- The survival of an animal is dependent on its successful defence against these invaders and
cancers.
- To ensure an effective response, the body has multiple defence systems that overlap and
interlink.
- The different layers/components of the immune system must be able to interact effectively.
- A key feature of the immune system is the coordination and communication that occurs
etee the diffeet opoets ad playes.
- The end result of an immune response is the elimination of the invader and the
deelopet of iuologial eoy
- This ensures that the next time the body encounters that particular invader, the immune
responses will be stronger and faster (I.e. There is a state of immunity against that agent.)
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Document Summary

Earliest reference to immunity, earliest use of vaccines, earliest understanding of the specificity of the immune response. The body is under continual attack from invading organisms (viruses, bacteria, parasites) The survival of an animal is dependent on its successful defence against these invaders and cancers. To ensure an effective response, the body has multiple defence systems that overlap and interlink. The different layers/components of the immune system must be able to interact effectively. A key feature of the immune system is the coordination and communication that occurs (cid:271)et(cid:449)ee(cid:374) the diffe(cid:396)e(cid:374)t (cid:272)o(cid:373)po(cid:374)e(cid:374)ts a(cid:374)d (cid:858)playe(cid:396)s(cid:859). The end result of an immune response is the elimination of the invader and the de(cid:448)elop(cid:373)e(cid:374)t of i(cid:373)(cid:373)u(cid:374)ologi(cid:272)al (cid:858)(cid:373)e(cid:373)o(cid:396)y(cid:859) This ensures that the next time the body encounters that particular invader, the immune responses will be stronger and faster (i. e. There is a state of immunity against that agent. ) Coordination of the many millions of cells involved in the immune response requires a complex coordination system.

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