DENT3060 Lecture Notes - Lecture 11: Gums, Vascular Permeability, Histopathology
Document Summary
Inflammatory response to mature biofilm: capillary permeability, blood flow immune cells (pmns, macrophages, bc, tc) & proteins, oedema/swelling, hyperaemic/bop, redness. Clinical condition pristine gingiva normal/clinically healthy gingiva (initial stage) early gingivitis established gingivitis (established stage) periodontitis (advanced lesion) Pristine gingiva: constant flow of gcf: pmns, leukocytes, proteins (e. g. igs) Histopathological condition histopathological perfect (no signs of inflammation) initially inflammatory lesion early lesion established lesion with no bone loss/no apical epithelial migration established lesion with bone loss/apical epithelial migration from cej. Clinically healthy gingiva: 4 days of plaque accumulation: bacterial products infiltrate tissues, exudates of fluids, >flow gcf, migration pmns je tissue responds with >capillary permeability (dilation), chemotaxis of pmns. Early gingivitis: 7 days plaque accumulation: bacterial noxious products continue to infiltrate tissue responds with >dilation in dento-gingival plexus, >chemotaxis of pmns/lymphocytes,
