CHEE1001 Lecture 21: CHEE1001 Semester 1 UQ 2018 CourseNotes
Document Summary
Microbe/microorganism: microscopic things that have characteristics of life. Agent: thing that produces a certain effect such as disease. Isolate: to separate different lineages of microbes from each other in a growth medium. Actual observation and discovery of microbes was only possible following the invention of the microscope by leeuwenhoeck. Lazzaro spallanzani: found that boiling broth would sterilise it, killing and microorganisms in it. Pasteur: showed that weakened virus or bacteria can induce immunity. Heat-processing of food (e. g. milk) to kill pathogenic bacteria. Chemotherapy- paul ehrlich developed the guiding principle of chemotherapy, of selective toxicity (drug must be toxic to the infecting microbe, but relatively harmless to host cells). Bacteria- single celled organisms, with circular dna and no nucleus. Fungi- most are multi-celled; some are single celled (yeasts) organisms with nucleus and mitochondria. Protozoa- single celled organisms with nucleus and other membranous organelles. Viruses- infectious particles made of dna or rna, protein, sometimes lipid membrane.