BIOM3010 Lecture Notes - Lecture 1: Chordae Tendineae, Pulmonary Artery, Venous Blood

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4 Aug 2018
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Made up of cardiomyocytes specialised muscle cells. Main function pump blood through circulatory systems. 2 sets of valves: atrioventricular tricuspid and mitral, semilunar aortic and pulmonic. Enable forward blood flow + prevent backwards flow. Cardiac valves open if pressure behind is greater than pressure in front. Chordae tendineae prevent the valves from everting when the ventricles are contracting: papillary muscles where attached to heart. Cycle of contraction and relaxation: venous flow arrives in right ventricle, venous blood sent in lung via pulmonary artery, oxygenated blood returns to left atrium, oxygenated blood enters left ventricle, oxygenated blood sent in arteries to tissue. Isovolumetric ventricular contraction: ventricular filling, ventricular ejection. At rest, atrial filling makes small contribution (30%) to ventricle filling. High hr (cid:415)me for passive lling decreases: atrial pumping makes much larger contribution to ventricle filling under these conditions. Tp interval decreases (p-t only decreases in pathological conditions)

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