BIOM2071 Lecture Notes - Lecture 10: Luteinizing Hormone, Posterior Pituitary, Anterior Pituitary

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11 Apr 2019
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Endocrine system in reproduction: hormones control many aspects of reproduction, hypothalamus anterior pituitary ovary/testis/uterus/breast, hypothalamus posterior pituitary uterus/breast. Testosterone in male reproduction/sexual activity: regulates physiological changes related to hair location/growth, strength, cognition, aggression/competitiveness, vocal changes, reproductive system and libido, can be reduced by metabolic syndromes/diabetes. Increases enos and nnos activity (both produce nitric oxide required for erection), involved in ejaculation and supports spermatogenesis: low concentration = erectile dysfunction, sexual activity = increased production. Ovarian cycle: follicular phase: maturation of follicles and ovulation, luteal phase: formation and subsequent degeneration of corpus luteum. Gh, tsh, melatonin (sleep) and insulin (metabolic health: during menstruation: prepares endometrium for implantation, both regulate physiology of cervix and vagina. If implantation does not occur: hcg not produced from placenta, corpus luteum regresses to become. Primordial follicles: produced in utero and lost throughout life (6 million at 5th month gestation, 1-2 million at birth, 300,000 at puberty onset, only 400-500 destined for ovulation.

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