BIOM2015 Lecture Notes - Lecture 9: Tocopherol, Neuroprotection, Statin
Saturday, 5 May, 2018
Can we Prevent Dementia
Ageing human population
Life expectancy expect to increase
Understanding disease with ageing
Lengthen human life in animal study
Yeast in animal, mutate, adjust, enhance life span, research found worm has
gene with longer life span
caloric restriction reducing calorie intake relief work of CVS
drugs respiratory slow raging process mimic calorie restrict model
To lengthen age, anti ageing drug, exercise and lifestyle
fasting and caloric restriction, genetic and stem cell nanaotech , potential drugs
causes of death influenza antibiotic change modality
turbiculosis infection causes diarrhea GI issue heart disease cerebral vascular
disease 2010 death rate significantly drop cancer and CVS takes up
Higher median income, higher education, healthy diet, managing stress better
longer life spans
due to better access to health care services, better quality of food, less risk
exposure to higher chemical world
Contribute to long lifespan
Diet and exercise CV health
antioxidant
DNA chromosome tips darken telomeres functions as cap like shoe laces as cell
divide telemeres naturally shorten moderate number of time undergo mitosis
too short cells age and die
diseases links to telemerase helps to maintain telemeres degrading over time
telemerase protect ends of DNA leading longer lifespan delay cell death
cancer cells elevated telomerase all the time so more relocation highly function
telomerase
theraputic tool is to address telomeres
abundant telomeres addition and shortening tail slowing reduce extend and
telemersae missing, mitosis cell division stops
support inflammation mitochondrial function
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Document Summary
Yeast in animal, mutate, adjust, enhance life span, research found worm has gene with longer life span caloric restriction reducing calorie intake relief work of cvs drugs respiratory slow raging process mimic calorie restrict model. Higher median income, higher education, healthy diet, managing stress better longer life spans due to better access to health care services, better quality of food, less risk exposure to higher chemical world. Telemere story (genetic and env factories and supporting telomeres activity) Food promotes blueberries beets sh salmon garlic broccoli cancers of organs have less telomeres exercise and telemeres altheletes and non-smokers exercise affect length profession linked to telomerase activity cause and effect healthy active lifestyle stabilise protect dna. Wbc ghting infection immune bene t anti ageing and exercise. Mg vit c d promote telemeres dont smoke avoid re ned card get good sleep cv bene t and anti ageing.
