BIOC2000 Lecture Notes - Lecture 33: Acetyl-Coa, Citric Acid Cycle, Electrochemical Gradient
Friday, 25 May, 2018
TCA cycle
TCA / Citric Acid Cycle / Krebs’ Cycle
-located in mitochondria
-glucose fat protein centralised to pyruvate for TCA cycle entering
-Amphibolic (making and breaking role; synthesis and knocking over)
-where is it in the cell embedded in interior if mitochondria
-breaking down of fat in mitochondria; some cytosolic some mitochondrial some urea
cycle
-NADH glycolysis and Kreb’s cycle
-how we loss Co2 and ETC
-making ATP
-different process
-glycolysis in terms of oxidising our food we are in cytosol how ensure enter
mitochondria
-transporter embedded in membrane acting as specific pore to enter molecules
-double membranous structure membrane enclosing mitochondria
-charge things do not like to cross mitochondria
-inner plasma membrane is tight
-pyruvate translocate move protons and pyruvate across cytosol to mitochondria
-1 gradient to transporter co transport effort low on the increase efficiency to
mitochondria
-proton gradient generated
-pri entering s acetyl CoA
-active protein jammed together to drive conversion
-enzymes taking 2 C pyruvate to acetyl CoA by losing 1 CO2
-acetyl CoA means to tag/label Carbon entity such cells can utilise it it is a big
molecule alanine Vit B5
1
Document Summary
Tca / citric acid cycle / krebs" cycle. Glucose fat protein centralised to pyruvate for tca cycle entering. Amphibolic (making and breaking role; synthesis and knocking over) Where is it in the cell embedded in interior if mitochondria. Breaking down of fat in mitochondria; some cytosolic some mitochondrial some urea cycle. Glycolysis in terms of oxidising our food we are in cytosol how ensure enter mitochondria. Transporter embedded in membrane acting as speci c pore to enter molecules. Charge things do not like to cross mitochondria. Pyruvate translocate move protons and pyruvate across cytosol to mitochondria. 1 gradient to transporter co transport effort low on the increase ef ciency to mitochondria. Active protein jammed together to drive conversion. Enzymes taking 2 c pyruvate to acetyl coa by losing 1 co2. Acetyl coa means to tag/label carbon entity such cells can utilise it it is a big molecule alanine vit b5.
