PSYC1011 Lecture Notes - Lecture 6: Diazepam, Anxiolytic, Cannabinoid
22 Aug 2018
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The study of drug effects on the nervous system and behaviour: mood, sensation, cognition. What is a drug: an exogenous chemical that significantly alters the function of cells in the body when taken in low doses, not required for normal cellular functioning, prescription drugs, non prescription drugs, legal/licit illegal/illicit. Initially coco-cola contained coca leaves: cocaine and heroin have been freely available. Intraperitoneal (ip): into the gut (used in animal research: subcutaneous (sc): under the skin. Inhalation: drug into the lungs: topical: absorbed through skin, oral: via the mouth. Antidepressants: major depressive disorder, depressed mood, anhedonia, early treatments were stimulants or depressants. In the early 1950s researchers were trialling new drugs for tuberculosis. Improved mood was noted: monoamine oxidase inhibitor, prevent breakdown of monoamine neurotransmitters, tricyclic antidepressants, the first tricyclic antidepressants were developed in the late 1950"s. Inhibited reuptake of 5-ht and ne: more 5-ht and ne signalling, selective serotonin reuptake inhibitors (ssris, were released in later 1980"s.
