BVB212 Lecture Notes - Lecture 2: Diazepam, Endorphins, Beta Blocker

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Handout: don"t memorise the handout, but learn a few! Steroids - pellet or injection (food residue) long half-life: b-agonists - orally active (food residues) long half-life, peptides - injection - ideal for animals, low half-life (good for human consumption) Assignment: when could they detect it in humans/animals, you can"t pick it as easily on mass spec, they were big. Ihf-1 levels go insane if horses have growth hormones, whereas controls did not, so by measuring this you could detect doping (horses-200-600 igf, they"re inbred so their genetics are close) In humans, levels are 50-1000 without any injected gh, some people are just born that way, so it can still be hard to test in humans. Anabolic compounds: how do they work: they do increase muscle, but do they make you stronger, testosterone and clenbuterol - stronger, muscle wise, but they"d get tired very quickly, as they endurance is shitty.

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