POPH20001 Lecture Notes - Lecture 9: Antiplatelet Drug, Personalized Medicine, Ischemia
30 Jul 2018
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Document Summary
Precision in medicine (cid:498)precision medicine(cid:499): the tailoring of medical treatment to the individual. Stratify individuals into subpopulations that differ in susceptibility characteristics of each patient to a particular disease, biology and/or prognosis of diseases they may develop, or in their response to a specific treatment. Concentrate preventive or therapeutic interventions on those who will benefit, sparing expense and side effects for those who will not: other terms: personalized medicine, stratified medicine. Pythagoras (circa 582 500 bc) (cid:498) dangers of some, but not others, individuals who eat the fava bean (cid:499) Haemolytic anaemia in response to ingestion of fava (broad) beans. How to stratify: marry these factors together in order to treat. History of pharmacogenomics: most of work looking around drug metabolizing genes. Definitions: pharmacogenetics and pharmacogenomics (broad) are often used inter- changeably, european medicines agency. Pharmacogenetics is the study of interindividual variations in. Dna sequence related to drug response - variations in the genome itself.
