PHYS30001 Lecture Notes - Lecture 25: Plasma Osmolality, Hemoglobin, Umbilical Vein
Document Summary
However: renal tubules retain na+ & water to maintain blood/plasma volume expansion. Filtration of water & solutes (glucose, protein, amino acids, urea, calcium: urine flow & volume. Water & salt retention: fills vascular spaces achieved by svr & allows accumulation. Plasma osmolality: haemodilution - measure of concentration of molecules such as. In pregnant women: plasma osmolality by 5th week of pregnancy (early) & is 10 mosmol/kg than preconception values by 10th week, changing little thereafter. sodium, chloride, potassium, urea, glucose & other ions in blood. Substitutes for fetal organs: lungs, kidneys, gastrointestinal tract. Provides fetus with oxygen and nutrients (and waste removal). Inadequate adaptations in mother can compromise placental function. Mother"s blood vessels break during invasion/implantation to form blood lakes (not affected by vasoconstrictors so placental blood flow not compromised) Left and right ventricles function in parallel to perfuse body and placenta. Adults - 2 separate circulatory systems, pulmonary and systemic. Fetus curve shifted left, functions at lower oxygen saturation.
