NEUR30004 Lecture Notes - Lecture 14: Afferent Nerve Fiber, Retina, Dynorphin

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We can classify inputs depending on anatomical criteria like myelinated or unmyelinated there are also response properties. What the investigator propose is we have seperate activation of two components of the spinothalamic tract pathway. With cold it depends on the balance of the cold and noxious cold pathways. What you use them for is inject them to the brain stem and nerve terminal will take it up and trasfer to the neuronal cell body on the right you can see red and green and yellow neuonrs. What this type of study did is look at spinal projections from lamina 1 to the rbain stem compared to the thalamus there are 400 neurons in the lumbar region, the outpiuts werent going to the thalamus. When we consider fear response the major brain response is the amygdala complex which has two parts which is the cortical and central amygda part cortical receives input and central is output looking at these regions.

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