NEUR30004 Lecture Notes - Lecture 4: Histology, Terabyte, Genomics

• School: University of Melbourne
• Department: Neuroscience
• Course: NEUR30004
• Professor: Peter Kitchener

Document Summary

* the set of all connections in a brain, or sub-region, is (by virtue of insidious and deliberate trends in technical jargon) the connectome. Connectome is the data that describes all the connectivity between different bits of the nervous system. * given that there might be 1015 connections/synapses in the human brain, we might need to look at bigger, less detailed pictures of connectivity. The macro-scale (whole brain connectivity at this level what connects to what) The meso-scale (interconnections between regions of neurons, as high resolution as which neurons connects to which region) most common as it is pretty much what you see when you look through a microscope. The micro-scale every synapse, in all their synaptic variety. * and, of course, ultimately such maps should seamlessly integrate the morphological and functional properties of connectivity. So, we need a morphological and a functional description of every connection in the nervous system.