NEUR30002 Lecture Notes - Lecture 4: Depolarization, Sodium Chloride, Goldman Equation
13 Aug 2018
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Fast inhibitory transmission inotropic receptors ii inhibition. We talkied about excitation where glutamate is the key contributer inhibitory amkes it less likely to fire an ap gaba comes form glutamate it is then packaged into vesicles where it is preped for synaptic release through ca. Gaba is released, binds to recepor of ligand gated ion channel. Gaba is taken back up by glial where it is not recylced but then taken to the repiratory cycle thats the cycle for gaba. Gaba is the predomentant inhibitory glycine is more important in the spinal cord they are both effective throughout the brain glycine comes from serine, the transporter puts its into vesicles and then it is released. Gaba opens the cl channel and stops the firing of ap. For cl-, it wants to be at -65 any deviation will change the direction og cl flow into our outside the cell there are clasess of ligand gated ion channels.
