MEDI40004 Lecture Notes - Lecture 13: Hydrocephalus, Embolectomy, Glibenclamide

• School: University of Melbourne
• Department: Medicine
• Course: MEDI40004
• Professor: Rodney Luwor

Document Summary

Ischemia -> progress of ischemia can cause loss of electric function and decreases ap, causes speech problems etc. (below 20) -> ischemia penumbra. Shows the symptoms, what is happening internally, diagnosis. Delayed ttp in the context of vessel occlusion = leptomeningeal collateral supply and confirms the presence of stroke. Lacunar infarct left thalamus: lenticulostriate artery due to high blood pressure and lipohyalinosis (high cholesterol) -> breakdown of the plaque and become embolus. Stroke vs tia: duration of tia is 10 minutes. Tia: high risk emergency, 10% stroke in first week, urgent assessment and treatment, no stenosis or atrial filbration (ecg and carotid imaging, start antiplatelet, high potent statin, antihypertensive, reduced the relative risk of stroke by 80% All stroke types and severities: stroke unit care, complication prevention, secondary and tertiary complications, reduce morbidity and mortality for all stoke subtypes and severitites, early commencement of rehabilitation. Ischemic stroke: dissolving the embolus <4. 5hr od the occurrence (tpa)