CEDB20003 Lecture Notes - Lecture 13: Dynein, Atp Hydrolysis, Integrin
13 Aug 2018
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Document Summary
Network is ideal as a transportation network since it covers a large area of the cell. Roads are quite static, cytoskeleton is very dynamic. 3 dimensional range can be modified quite efficiently over a short period of time. Ideal to transport certain cargos into certain areas. Khc comprises a globular n terminal head domain, which binds to microtubules and has. Atpase activity, a central a-helical neck and stalk, which mediate khc dimerisation, and a c terminal tail region. Kinesins member of large family that is part of nearly all eukaryotic species. C terminal end which interacts with the cardo of the kinesis light chains that have a specificity on which type of cargo it carries. Kinesis 5 can form homotetrameric comlexes the two coiled domains can slide along each other. Kinesins are an example of a motor protein atp fuelled movement.
