BIOM30001 Lecture Notes - Lecture 17: Obstructive Lung Disease, Allergic Rhinitis, Silicosis
16 Oct 2018
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Document Summary
6l/minute air breathed for a typical 70kg person. Respiratory system is incredibly exposed to the environment. Air that reaches back of pharynx is ltered, humidi ed and warm. Measuring lung function: hallmark of obstructive airway disease = reduced fev1 compared to normal fvc. Note: fev1 is max air expelled in 1 second, fvc is total expelled vital lung capacity. Lung disease: a global context: total lung disease = 13. 7% of deaths; ~7. 5 million deaths/year, air pollution, smog, asbestosis, silicosis, gas leaks, mining, deforestation etc are all relevant global markers of increasing lung disease. What is asthma: variable air ow obstruction, in ammation and remodelling from onset of asthma thickened basal layer (submucosal in ammation, hyper-responsiveness diagnosis is made for reversibility. People su ering from rhinitis (hay fever) have 3. 16 times higher risk of asthma compared to those never having allergic rhinitis. 21 november 2016 big storm made pollen in air way worse.
