BIOM30001 Lecture Notes - Lecture 1: Blood Sugar, Insulin Resistance, Blood Pressure

• School: University of Melbourne
• Department: Biomedicine
• Course: BIOM30001
• Professor: Terry Mulhern

Document Summary

A syndrome is a collection of symptoms perhaps without a single pathogenesis. Metabolic syndrome is a cluster of risk factors for cardiovascular disease and type 2 diabetes mellitus, which occur together more often by chance alone. These factors are: excess abdominal weight, lipid abnormalities, hypertension (high bp, elevated glucose levels. Other names include: syndrome x(+), dysmetabolic syndrome, insulin resistance syndrome, plurimetabolic syndrome, cardiometabolic syndrome, dyslipidaemic syndrome, hypretriglyceridaemic waist and deadly quartet. Clinical criteria for metabolic syndrome = (any 3 of these 5: large waist circumference, a high triglyceride level, a low hdl cholesterol level, high blood pressure, high fasting blood sugar. Triglycerides in blood are coated with lipoproteins (which vary in size and density. Hdl lipid droplets are low density (and small) It falls when the heart relaxes and re lls with blood, a cycle called diastole: systole is the top number and diastole is the bottom number.