BIOM30001 Lecture Notes - Lecture 14: Cell Potency, Blastocyst, Cornea

• School: University of Melbourne
• Department: Biomedicine
• Course: BIOM30001
• Professor: All

Document Summary

L14 stem cell science and regenerative medicine - ethical implication, societal expectations. Source of stem cells matters: ethics and regulatory differences, how consent is obtained and from whom varies. Heightened public expectation in stem cell science: exaggerated perception of benefit, little acknowledgement of risks, pate(cid:374)ts (cid:373)a(cid:455) feel (cid:862)ste(cid:373) (cid:272)ells(cid:863) are their o(cid:374)l(cid:455) optio(cid:374) (cid:271)ut (cid:272)osts (cid:373)a(cid:455) e(cid:454)te(cid:374)d (cid:271)e(cid:455)o(cid:374)d financial. Clinical translation of promising science progressing but will take time. Largel(cid:455) u(cid:374)regulated (cid:272)o(cid:373)(cid:373)er(cid:272)ial i(cid:374)terests dri(cid:448)i(cid:374)g (cid:862)ste(cid:373) (cid:272)ell(cid:863) i(cid:374)dustr(cid:455) rather tha(cid:374) s(cid:272)ie(cid:374)tifi(cid:272) evidence: potential to undermine legitimate translation and need for clinical research. Is it ethical to do research no matter the source: esc pluripotent: from pre-implantation blastocyst icm killing the embryo, multipotent adult stem cells: foetal or adult tissue such as brain. Concern about the sanctity of life and reproductive technology ips pluripotent: from human somatic cells. If the(cid:455) do(cid:374)"t (cid:449)ill their treat(cid:373)e(cid:374)t (cid:271)e compromised: co(cid:374)(cid:272)er(cid:374) that ivf e(cid:373)(cid:271)r(cid:455)os are (cid:862)far(cid:373)ed(cid:863) for spare parts dolly ivf human, slippery slope to cloning.