BCMB30011 Lecture Notes - Lecture 27: Competitive Exclusion Principle, Peristalsis, Succinic Acid
Document Summary
* in the 20th & 21st century there have been remarkable improvements in the control of infectious diseases such as tuberculosis as a result of the development of antibiotics and immunisation and the provision of detective health delivery services. * family size association with allergy david strachan, 1989. * extended to: cleanliness, vaccination, antibiotic use will also have the effect of reduced exposure to infectious agents and dysregulated immune response. * the hygiene hypothesis is that you need some exposure to pathogens to prime your immune system and that protects against the development of allergies and potentially autoimmune responses. * graham rook (2003) said that you need to be exposed to microbes, not specifically infectious pathogens, in order to prevent the development of allergies or autoimmune responses. * humans are dependent on microbes for immune system development & function. * diet directs the development and function of the immune system.