BCMB20002 Lecture Notes - Lecture 4: Acetyl Group, Lactose Intolerance, Lipoic Acid

• School: University of Melbourne
• Department: Biochemistry and Molecular Biology
• Course: BCMB20002
• Professor: Terry Mulhern

Document Summary

* a lot or organisms get energy from anaerobic metabolism. * some of our tissues from our body are obligate anaerobes including the tissue of the eyes and red blood cells. * retina: relies mostly on anaerobic glycolysis for atp production few blood vessels in fovea centralis (centre of visual acuity) no mitochondria at some nerves and others only have very few mitochondria(mitochondria are deleted because they absorb light) * red cells: - delete nucleus and mitochondria when they mature. Anaerobic glycolysis essential to maintain red cell membrane integrity (failure=haemolysis) Contribute to constant lactate present in the blood. The entry of fructose and galactose into glycolysis: * fructose (from sucrose) from fat tissue can be converted into fructose-6p. The liver also converts fructose in the liver into fructose-1p. Almost, all fructose is metabolised in the liver. * what controls the fed state/release of insulin is the amount of glucose-6p a cell is generating.