DASC20010 Lecture Notes - Lecture 24: Growth Hormone–Releasing Hormone, Posterior Pituitary, Anterior Pituitary

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Increase uterine smooth muscle contraction: maternal behavioural modifications, functions . Anterior pituitary: growth hormone, thyroid-stimulating hormone, adrenocorticotropic hormone, prolactin, follicle stimulating hormone, luteinizing hormone. Hypothalamic stimulatory & inhibitory peptides: growth hormone releasing- hormone, growth hormone inhibiting hormone, thyrotrophic-releasing hormone, corticotrophin-releasing hormone, gonadotropic-releasing hormone, prolactin-releasing hormone, prolactin-inhibiting hormone. Hypothalamic-anterior pituitary regulation: multi-hormonal level system, may have negative or positive feedback effect. Growth hormone: regulation of secretion, target tissues, major effects. Stimulation of hormone: stress, exercise, blood glucose, decrease in blood fatty acids, body- under metabolic demand- have stimulatory effects on hypothalamus, stimulation- mainly get ghrh, then stimulates the release of growth hormone- then negative feedback- release ghihs. Growth hormone: growth effects: increased proliferation of cartilage cells via. Cortex: outer part, makes up about 80, consists of three layers, zona glomerulosa- outermost layer, zona fasciculate- middle layer and larget, zona reticularis- inner most layer.

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