DASC20010 Lecture Notes - Lecture 12: Capillary Refill, Renal Function, Extracellular Fluid

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Dasc: fluid balance lecture: fluid ph and regulation. Lecture objectives: explain how fluid volume is controlled, explain how fluid osmolarity is controlled, explain how fluid ph is regulated. Fluid compartments: total body fluid (water): 60%bw. Icf: 40% (intracellular fluid: 2/3 of total body h2o, ecf: 20, subdivided primarily into plasma and interstitial fluid, lymph- minor ecf fluid, plasma: 5% (of ecf) Interstitial and trans-cellular: 15: can use these to check of taking too much blood will affect the animal, fluid that isn"t in circulation or in the cell- it is around the cells, newborn: +20% ecf, more ecf- extra. Intracellular icf: can move in and out- and responsible for controlling osmolarity, anions: po4. 3-, protein anions, other: basically fixed inside the cell, other: urea and glucose. Tends to be a slight drift from plasma into interstitial fluid and into the icf. By regulating the na- help keep ecf at the right level. 300 mosmols/ml: normal in most cells and ecf.

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