ANTH106 Lecture Notes - Lecture 8: Dopamine Receptor, Fentanyl, Hallucinogen
Document Summary
Integration of information coming into cells from other neurons. All or none law if the overall increase in positive charge exceeds excitability threshold of -55mv, an action potential will occur. Positive charge is called an excitatory post synaptic potential (epsp) Negative charge is called an inhibitory post synaptic potential (ipsp) If more epsps and few ipsps enter a neuron, an action potential will fire. If more ipsps and few epsps enter a neuron, an action potential is inhibited. Typically formed between an axon terminal and a dendritic spine (axo-dendritic) Synapses can also form between an axon terminal and soma (axo-somatic) and with another axon (axo-axonic) When the action potential reaches the axon terminal, it causes: Once docked, vesicle content is emptied into synapse (exocytosis) Neurotransmitters cross the synapse and blind the receptors on postsynaptic cell. Vesicles (containing neurotransmitters) are moved to the membrane and dock. Binding of neurotransmitter to subunit causes subunits to move to create a channel.