1001NSC Lecture Notes - Lecture 5: Homeostasis, Higher Consciousness, Grey Matter

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week 5 part 2!
Neurotransmitters of love:
Lust: the craving for sexual gratification. Driven by testosterone and oestrogen
Attraction: characterised by euphoria when things are going well
High dopamine and adrenaline levels
Person with OCD shows the exact same profile
Same parts of the brain overactive, lasts approx. 2-6 months
Attatchment: sense of calm, peace, stability
High levels of oxytocin.
Getting dumped: feelings of anger and despair
Neurophysiology: relies of changes in cell membrane potential
Membrane potential results from an unequal electrical charge distribution, outside the nerve cell
is more positive than inside the cell
Signal (impulse) transmission: involves two types of membrane potential changes at two distinct
sites:
Local potential: the receptor/synaptic potential (at synapse or specialised nerve receptor
At receptor cell via sensory input (eg. flavour chemicals on taste buds on tongue), or at
nerve synapse via release of neurotransmitter)
KNOW FOR EXAM
Action potential: down enter length of nerve axon
Lots of local potentials building up until it gets to the threshold, the trigger potential. Huge
surge of nervous charge in membrane potential spreading down entire length of axon.
Triggers “all or nothing effect”: effect is exactly the same start to end, doesn’t slow down. Is
sustained with time and distance
Local and action potentials involve two events: (both potentials involve both)
Depolarization: membrane potential becomes more positive than -70mV (the norm. all the
way up to +30mV)
Repolarization: membrane potential returns to resting normal (-70mV)
Depolarisation and repolarisation are caused by the opening/closing of two types of ion
channels in the cell membrane:
Chemical-gated channels (controlled by chemicals [neurotransmitters])
Voltage-Gated channels (controlled by electrical change, open and close in response to
change in membrane potential)
Neuronal events:
1. Stimulus (neurotransmitter) causes brief opening of
chemically-gated Na+ channels. Na+ ions enter cell
(causes local potential).
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Document Summary

Attraction: characterised by euphoria when things are going well. Person with ocd shows the exact same pro le. Same parts of the brain overactive, lasts approx. Neurophysiology: relies of changes in cell membrane potential. Membrane potential results from an unequal electrical charge distribution, outside the nerve cell is more positive than inside the cell. Signal (impulse) transmission: involves two types of membrane potential changes at two distinct sites: Local potential: the receptor/synaptic potential (at synapse or specialised nerve receptor. At receptor cell via sensory input (eg. avour chemicals on taste buds on tongue), or at nerve synapse via release of neurotransmitter) Action potential: down enter length of nerve axon. Lots of local potentials building up until it gets to the threshold, the trigger potential. Huge surge of nervous charge in membrane potential spreading down entire length of axon. Triggers all or nothing effect : effect is exactly the same start to end, doesn"t slow down.

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