DOH133 Lecture Notes - Lecture 5: Glycogen, Dental Caries, Flaccid Paralysis
Describe five ways that saliva modulates bacterial growth
Waste removal – The physical flow of saliva helps remove disease-causing bacteria
from teeth & soft
oral surfaces
Barrier & Buffer agent – saliva contains buffering systems that help neutralize
acidic content
Fostering healthy plaque biofilm – development of pellicle, supports the attachment of
free-flowing
bacteria. The more bacteria attach to one another, creating large clumps that are easier
to swallow
and eliminate
Mineralisation – saliva rich in inorganic ions – high levels of F- are bacteriostatic
Antibacterial properties – lysozyme – causes bacterial cell lysis
Commercial sterilization?
Sterilization kills or removes all organisms and their spores in a material or object
Indication of microbial spoilage
Swollen cans often indicate a spoiled product
Give the name of the bacterium that causes botulism
Clostridium Botulinum
Botulism is a serious illness that causes flaccid paralysis of muscles
What characteristic of the organism causing botulism increases its chances of surviving
the canning process?
Clostridium Botulinum releases the toxin that causes botulism as part of its natural
anaerobic process, meaning it multiplies in an oxygen free environment
Explain why some bacteria from the oral cavity are unculturable
- It is hard to replicate similar conditions of the mouth
- Some bacteria’s may not grow on a specific media
- Some bacteria live symbiotically – need the presence of other bacteria to survive
(symbiotic relationship)
- Streptococcus mutans is a term used to describe a collection of many cariogenic
species of bacteria, including S. Mutans Serotypes C,E,F. Differentiate Serotype
from species.
- A serotype is a distinct variation within a species of bacteria or virus or among
immune cells of different individuals, these are classified together based on their
Document Summary
Describe five ways that saliva modulates bacterial growth. Waste removal the physical flow of saliva helps remove disease-causing bacteria from teeth & soft oral surfaces. Barrier & buffer agent saliva contains buffering systems that help neutralize acidic content. Fostering healthy plaque biofilm development of pellicle, supports the attachment of free-flowing bacteria. The more bacteria attach to one another, creating large clumps that are easier to swallow and eliminate. Mineralisation saliva rich in inorganic ions high levels of f- are bacteriostatic. Antibacterial properties lysozyme causes bacterial cell lysis. Sterilization kills or removes all organisms and their spores in a material or object. Give the name of the bacterium that causes botulism. Botulism is a serious illness that causes flaccid paralysis of muscles. Clostridium botulinum releases the toxin that causes botulism as part of its natural anaerobic process, meaning it multiplies in an oxygen free environment. Explain why some bacteria from the oral cavity are unculturable.
