MEDN2001 Lecture Notes - Lecture 10: Gallbladder, Bile Acid, Zymogen
Document Summary
Food broken down into absorbable molecules: secretion of juices. Propel ingested food from mouth toward rectum: absorption. Nutrients, electrolytes, and water are absorbed or transported from lumen of git to blood stream. Gi tract has the largest area of the body in potential direct contact with infectious, toxic, and immunogenic material. Approximately 80% of the immunoglobulin- producing cells are found in the small intestine. Digestion renders ingested food into absorbable forms. Involves the orchestrated secretion of products that hydrolyze chemical bonds in macromolecules and solubilize fats. Chief cells produce pepsin(ogen)s: exocrine pancreas: produces zymogens and bicarbonate. Zymogen - precursor for enzymes (like tripsin, dnanucleases) Bicarbonates neutralise stomach acids: liver: produces bile (bile salts and waste products) Solubilises fat content of food - breaking up into small droplets. The can be attacked by lipases and absorbed. Medn2001 page 1: the git has 3 layers of smooth muscle (musculature) "waves" of contraction - push food into the git.
