KINE 2475 Chapter Notes - Chapter 5.7: Caffeine, Minimally Invasive Procedures, Dutasteride

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Three categories of drug therapy: obstructive symptoms: slow urinary stream, intermittency, hesitancy, training to urinate, incomplete emptying, dribbling. Signs: digital rectal examination to reveal enlarge prostate (>20g) w/no nodules or indurations; prostate is soft, symmetric & mobile. Increase blood urea nitrogen (bun), serum creatine w/long-standing, untreated bladder outlet obstruction, elevated prostate-specific antigen (psa) level. Increase american urological association (aua) symptoms, decreased urinary flow rate (<10ml/s), increased pvr urine volume. Mild symptoms: asymptomatic or mildly bothersome symptoms, no complications of bph, watchful waiting. Have patient return for reassessment at intervals of 6-12 months: have patient complete standardized survey to assess severity of symptoms . Objective signs using urinary flow rate & pvr urine volume. Serious complications: surgical correction, transurethral, open prostatectomy, minimally invasive surgical procedure. Three categories of drug therapy: relax prostatic smooth muscle (reduce dynamic factor, a1-adrenergic antagonist. Relax the intrinsic spincter & prostatic smooth muscle to enahance urine flow. Improves urine capacity of bladder & increases intervals between voiding.

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