Question

choose the correct answer:

1. You discover a novel DNA-binding protein. what would be the best technique to identify other proteins that interact with your newly identified protein?

A. two-hybrid assay

B. ChIP-Seq assay

C. reporter gene assay

D. ChIP assay

2.Which of the following mechanisms illustrates a form of transcriptional repression that is unique to eukaryotes?

A. repressors blocking RNA polymerase by binding an operator site within the promoter

B. repressors recruiting enzymes to modify groups on histones to compact chromatin

C. repressors binding to a site near an activator binding site where they interact with and inhibit the activator

D. repressors recruiting enzymes to modify groups on histones to loosen chromatin

3.Which one of the following gene families is not under the control of a group of regulatory elements called a locus control region (LCR) or a global control region (GCR)?

A. human globin genes

B. mouse globin genes

C. mouse HoxD gene cluster

D. S. cerevisiae mating-type genes