Hydrophobic extracellular signaling molecules would most likelyinteract with ____________ in/on target cells.
A.
receptor tyrosine kinases
B.
intracellular receptors
C.
G protein-coupled receptors
D.
ligand-gated ion channels
E.
membrane transport proteins
0.5 points
Question 2
__________ signal(s) through enzyme-linked receptors where thereceptor is not itself a kinase but instead recruits cytosolickinases.
A.
Cytokines
B.
Insulin
C.
Adrenaline
D.
Neurotransmitters
E.
Thyroid hormones
0.5 points
Question 3
Which of the following is a post-translationalmodification that's oftentimes used to regulate proteinfunction within intracellular signaling cascades?
A.
Allosteric interaction
B.
Compartmentalization
C.
Second messenger system
D.
Assembly of protein complexes
E.
Ubiquitination
0.5 points
Question 4
___________ is a common type of "allosteric switch" proteinwhich gets directly activated by intracellular calcium.
A.
GTP-binding protein
B.
Kinase
C.
Calmodulin
D.
Phosphatase
E.
Heterotrimeric G protein
0.5 points
Question 5
When a small GTP-binding protein (GBP) is in the "on" (active)state (select any/all answers that apply):
A.
its Switch I and Switch II domains tilt toward one another.
B.
the GBP can physically interact with downstream effectormolecules.
C.
GDP is bound within the nucleotide-binding pocket of theGBP.
D.
the GBP is incapable of hydrolyzing its bound GTP.
E.
the Switch II domain is phosphorylated on multiple tyrosineresidues.
Hydrophobic extracellular signaling molecules would most likelyinteract with ____________ in/on target cells.
A. | receptor tyrosine kinases | |
B. | intracellular receptors | |
C. | G protein-coupled receptors | |
D. | ligand-gated ion channels | |
E. | membrane transport proteins |
0.5 points
Question 2
__________ signal(s) through enzyme-linked receptors where thereceptor is not itself a kinase but instead recruits cytosolickinases.
A. | Cytokines | |
B. | Insulin | |
C. | Adrenaline | |
D. | Neurotransmitters | |
E. | Thyroid hormones |
0.5 points
Question 3
Which of the following is a post-translationalmodification that's oftentimes used to regulate proteinfunction within intracellular signaling cascades?
A. | Allosteric interaction | |
B. | Compartmentalization | |
C. | Second messenger system | |
D. | Assembly of protein complexes | |
E. | Ubiquitination |
0.5 points
Question 4
___________ is a common type of "allosteric switch" proteinwhich gets directly activated by intracellular calcium.
A. | GTP-binding protein | |
B. | Kinase | |
C. | Calmodulin | |
D. | Phosphatase | |
E. | Heterotrimeric G protein |
0.5 points
Question 5
When a small GTP-binding protein (GBP) is in the "on" (active)state (select any/all answers that apply):
A. | its Switch I and Switch II domains tilt toward one another. | |
B. | the GBP can physically interact with downstream effectormolecules. | |
C. | GDP is bound within the nucleotide-binding pocket of theGBP. | |
D. | the GBP is incapable of hydrolyzing its bound GTP. | |
E. | the Switch II domain is phosphorylated on multiple tyrosineresidues. |