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A metastasis is

a) a secondary tumor in a different part of the body that arises from a cell from the primary tumor

b) a cell that is dividing in defiance of normal constraints

c) a part of the primary tumor that has invaded the surrounding tissue

d) the portion of the cancerous tumor that displays genetic instability

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Related questions

You are interested in studying lung cancer. You hypothesize that lung tumor growth is due to deletion of a gene required to stop the cells from dividing uncontrollably. You have both wild type and tumor lung tissue. Which of the following experimental approaches would be a definitive test of your hypothesis? EXPLAIN

a) Western blot comparing wild type and tumor cells.
b) Southern blot comparing wild type and tumor cells.
c) Northern blot comparing wild type and tumor cells.
d) PCR using genomic DNA prepared from wild type and tumor cells.

Cancer biologists use principles of evolution to understand the development of tumors. A population of cells can obtain a mutation after exposure to a carcinogen. In some of the cells, the mutation is not repaired by the cell’s DNA repair machinery and is retained in the genotype. Only a fraction of the cells retaining the mutation become cancerous and only a fraction of those cells have the ability to form a tumor – cells that grow much faster than normal body cells. From the perspective of a tumor-causing cell, what evolutionary processes are at work? From the perspective of the body harboring these tumor cells, what evolutionary processes are at work?

Cancer biologists use principles of evolution to understand the development of tumors. A population of cells can obtain a mutation after exposure to a carcinogen. In some of the cells, the mutation is not repaired by the cell’s DNA repair machinery and is retained in the genotype. Only a fraction of the cells retaining the mutation become cancerous and only a fraction of those cells have the ability to form a tumor – cells that grow much faster than normal body cells. From the perspective of a tumor-causing cell, what evolutionary processes are at work? From the perspective of the body harboring these tumor cells, what evolutionary processes are at work?

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