Question

5. Which of the following statements regarding eukaryotic transcription is FALSE?

a. RNA polymerase II has a critical carboxy-terminal domain that is phosphorylated during

active transcription.

b. General transcription factors are designated TFII followed by a number, and they function in initiation of transcription across the eukaryotic genome.

c. The most highly transcribed eukaryotic genes contain CpG islands upstream of their transcription start site rather than TATA boxes.

d. Distal enhancers, like promoter-proximal elements, are composed of several small, 6–10 bp functional sequence elements.