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20 Nov 2019
MULTIPLE CHOICE. Choose the one altermative that best completes the statement or answers the question. 1) Which of the following is/are a major difference between skeletal and smooth muscle contraction? 1) A) Use of the protein actin in the process B) Use of ATP in the contraction proces C) Use of calcium in the contraction process D) Whether or not contraction can be directly initiated by hormone signaling E) More than one is correct 2) 2) The function of T-tubles (transverse tubules) is to A) rapidly conduct action potentials to the interior of a muscle fiber B) store Ca2+ ions inside the muscle fiber. C) conduct ATP molecules out of the mitochondria throughout the sarcoplasm D) ensure a supply of glycogen throughout the muscle sarcoplasm 3) 3) What is the primary role of titin protein in the sarcomere? A) Alignment of actin thin filaments B) Regulation of crossbridge formation C) Serving an an elastic element D) An activating co-factor for myosin kinase (ML.CK) E) None of the above 4) If you were to look at a cross-section of a sarcomere in the I-Band (but not the Z-disk), which) filaments would you see? A) Myosin thick filaments and cross-linking accessory proteins B) Only myosin thick filaments C) Both actin thin filaments and myosin thick filaments D) Only actin thin filaments E) Actin thin filaments and cross-linking accessory proteins 5) In what configuration would we see actin and myosin in the Rigor State? A) The myosin head would be flexed, and would be in tight association with actin; ADP only is B) The myosin head would be flexed, and would be in tight association with actin; No ATP (or C) The mysosin head would be flexed, and dissociated completely from actin. ATP is bound to D) The myosin head would be cocked, and would be in loose/weak association with actin: ATP is E) The myosin head would be cocked, in tight association with actin; ATP hydrolyzed to ADP present ADP, or Pi) present myosin. not hydrolyzed Pi
MULTIPLE CHOICE. Choose the one altermative that best completes the statement or answers the question. 1) Which of the following is/are a major difference between skeletal and smooth muscle contraction? 1) A) Use of the protein actin in the process B) Use of ATP in the contraction proces C) Use of calcium in the contraction process D) Whether or not contraction can be directly initiated by hormone signaling E) More than one is correct 2) 2) The function of T-tubles (transverse tubules) is to A) rapidly conduct action potentials to the interior of a muscle fiber B) store Ca2+ ions inside the muscle fiber. C) conduct ATP molecules out of the mitochondria throughout the sarcoplasm D) ensure a supply of glycogen throughout the muscle sarcoplasm 3) 3) What is the primary role of titin protein in the sarcomere? A) Alignment of actin thin filaments B) Regulation of crossbridge formation C) Serving an an elastic element D) An activating co-factor for myosin kinase (ML.CK) E) None of the above 4) If you were to look at a cross-section of a sarcomere in the I-Band (but not the Z-disk), which) filaments would you see? A) Myosin thick filaments and cross-linking accessory proteins B) Only myosin thick filaments C) Both actin thin filaments and myosin thick filaments D) Only actin thin filaments E) Actin thin filaments and cross-linking accessory proteins 5) In what configuration would we see actin and myosin in the Rigor State? A) The myosin head would be flexed, and would be in tight association with actin; ADP only is B) The myosin head would be flexed, and would be in tight association with actin; No ATP (or C) The mysosin head would be flexed, and dissociated completely from actin. ATP is bound to D) The myosin head would be cocked, and would be in loose/weak association with actin: ATP is E) The myosin head would be cocked, in tight association with actin; ATP hydrolyzed to ADP present ADP, or Pi) present myosin. not hydrolyzed Pi
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