Biology And Biomedical Sciences BIOL 2960 Lecture Notes - Lecture 38: Ob River, Genome Project, Inflammatory Bowel Disease
14 Aug 2018
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Study guide 15: cancer (lectures 38-39) and microbiome (lectures 40-41) Cancer cells have 2 heritable properties: they reproduce by escaping normal controls on growth and division: neoplastic new growth, they invade and colonize territories reserved for other cells. It can be passed on from an abnormal cell to its progeny: the implication is that there are genetic changes that distinguish a cancer cell from a normal cell. Carcinogenesis: the making of cancer (related to mutagenesis: chemical carcinogens and radiation, the correlation is clear. Mutagenesis: the making of mutations (related to carcinogenesis: lesions in dna repair genes promote cancer, tumors are clonal, transformed cells (note: this is different than transformed cells in cloning, the culture cell equivalent of cancer cell. Involved in signaling during the cell cycle: progression through the cell cycle is driven by cyclins, cyclins bind to and activate protein kinases (cyclin-dependent kinases. Microbial ecology: the study of interactions among microorganisms, with each other and with their environment.
