BIOL 2021 Lecture 15: Lecture 15
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The vesicles that transport materials from donor membranes to acceptor membranes include:
1. | COP-II coated vesicles | |
2. | COP-III coated vesicles | |
3. | COP-I coated vesicles | |
4. | Clathrin coated vesicles |
2.5 points
QUESTION 11
During skeletal muscle contraction, the roles of ATP include:
1. | ATP is not required for forming the crossbridges between myosin and actin filaments. | |
2. | ATP is utilized as a structural linker to mediate the interaction between myosin and actin filaments | |
3. | Hydrolysis of ATP provides energy for myosin head to move along actin filaments and the binding of ATP to myosin head allows the detachment of myosin fromactin filaments. | |
4. | ATP binds to actin filaments to drive the power stroke of myosin head. |
2.5 points
QUESTION 12
One of the functions of smooth endoplasmic reticulum is
1. | Synthesizing steroid hormone in the endocrine cells of the gonad and adrenal cortex | |
2. | Serves as the starting point of the biosynthetic pathway | |
3. | Synthesizing secretory proteins | |
4. | Degrading cell debris |
2.5 points
QUESTION 13
The function of COP-II coated vesicles is mainly:
1. | Transporting materials from endosomes to Golgi complex | |
2. | Moving materials from the ER to the ERGIC and Golgi complex. | |
3. | Transporting materials from Golgi complex back to endoplasmic reticulum. | |
4. | Involved in receptor-mediated endocytosis. |
2.5 points
QUESTION 14
Which of the following processes is completed in rough endoplasmic reticulum?
1. | Chaperones help misfolded proteins fold correctly. | |
2. | Proteins that target to nucleus are synthesized in rough endoplasmic reticulum. | |
3. | O-linked glycosylation occurs in rough endoplasmic reticulum. | |
4. | Misfolded proteins are destructed in rough endoplamic reticulum. |
2.5 points
QUESTION 15
Kinesin is the motor protein that coorporates with microtubules. It has the following functions:
1. | It uses GTP as energy source. | |
2. | It can hydrolyze ATP and use the energy to drive cargo along microtubules from minus end to plus end. | |
3. | It has a globular head that can act as GTPase | |
4. | The tail of kinesin is more diverse and binds to cargo |
2.5 points
QUESTION 16
For correct segregation and trafficking, lysosomal proteins are tagged in the cis-Golgi with phosphorylated mannose residues, and then the tagged lysosomal enzymes are recruited to clathrin coated vesicles by mannose 6-phosphate receptors.
True
False
2.5 points
QUESTION 17
The process that specialized cells, such macrophages, engulf relatively large particles is:
1. | Called pinocytosis | |
2. | Called phagocytosis | |
3. | Mediated by COP-II coated vesicles | |
4. | Called autophagy |
2.5 points
QUESTION 18
Proteins synthesized on rough endoplasmic reticulum and smooth endoplasmic reticulum are imported co-translationally to their destinations
True
False
2.5 points
QUESTION 19
Treatment of cells with a drug that promotes microtubule disassembly disperses Golgi complex into separate stacks of membrane compartments, suggesting that:
1. | Golgi complex is made of microtubules. | |
2. | Microtubules are important for the organization of Golgi complex. | |
3. | Microtubules are transported into Golgi complex | |
4. | Golgi complex is composed of tubulin proteins |
2.5 points
QUESTION 20
Which of the following is correct about signal sequence of a secretory protein?
1. | It is an âaddress codesâ for protein trafficking pathways | |
2. | It is usually located at the C-terminus. | |
3. | It targets the ribosome and the protein that is being synthesized to endoplasmic reticulum. | |
4. | It is removed in Golgi complex. |