BIO 3302 Lecture Notes - Lecture 5: Inositol, Carbonic Anhydrase, Teleost

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Topics to be covered: basic principles: Diffusion vs convection: blood gas transport, gas exchange organs, the control of ventilation. Di(cid:448)i(cid:374)g i(cid:374)tegrati(cid:374)g gas ex(cid:272)ha(cid:374)ge a(cid:374)d circulation. For aerobic metabolism, require o2 supply and co2 removal: o2 supply critical, co2 removal needed to avoid acid-base disturbance, diffusion adequate for animals <1mm diameter, high sa:v, low mr. Diffusion gradients drive gases; o2 moves from cell into gradient, partial pressure difference drive o2 from envt into animal: gas exchange organ plus circulatory system. Called the oxygen cascade (seeing o2 movt by a series of steps) Pathway o2 is going to take fallen partial pressure from envt to the mitochondria: ventilation supplies gas exchange surface with respiratory medium (air or water intake to gas exchange surface) Transfer of respiratory gases: diffusion of o2 and co2 across the respiratory epithelium. Thin layer of cells (0. 5 - 15 m)

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